Description

3-Fluoropyridin-4-Ol Hydrochloride is a high-purity fluorinated pyridine derivative, a crucial building block in modern organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with enhanced biological activity and specific physicochemical properties. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom can improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and liquid crystals for electronic and optical applications.
• Chemical Biology Probes: Utilized as a building block for fluorophore-tagged molecules and activity-based probes used in biochemical assays.

Basic Information

Product Name	3-Fluoropyridin-4-Ol Hydrochloride
CAS No.	1309602-71-8
Molecular Formula	C5H5ClFNO
Molecular Weight	149.55 g/mol
Synonyms	4-Hydroxy-3-fluoropyridine hydrochloride; 3-Fluoro-4-hydroxypyridine hydrochloride; 3-Fluoro-4-pyridinol hydrochloride; 3-Fluoro-4-pyridinone hydrochloride; 3-Fluoro-4(1H)-pyridinone hydrochloride; 3-Fluoropyridin-4(1H)-one hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Fluoropyridin-4-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.