Description

5,5-Difluoro-2-Oxocyclohexanecarbonitrile is a high-value, fluorinated cyclic ketone nitrile building block. This compound is critical for introducing difluoro and carbonyl functionalities into complex molecular architectures, enabling the synthesis of novel materials and active ingredients. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), leveraging the fluorine atoms to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and pesticides where the difluoro motif can enhance biological activity and environmental persistence profiles.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and coatings with unique thermal or chemical resistance properties.
• Organic Synthesis Building Block: Employed in cyclization reactions, nucleophilic additions, and as a scaffold for constructing complex heterocycles in academic and industrial R&D settings.
• Fluorine Chemistry Studies: A valuable compound for investigating new fluorination methodologies and the stereoelectronic effects of gem-difluoro groups.

Basic Information

Product Name	5,5-Difluoro-2-Oxocyclohexanecarbonitrile
CAS No.	1309602-28-5
Molecular Formula	C8H7F2NO
Molecular Weight	171.15 g/mol
Synonyms	5,5-Difluoro-2-oxocyclohexane-1-carbonitrile; 2-Oxo-5,5-difluorocyclohexanecarbonitrile; 5,5-Difluoro-2-oxocyclohexanecarbonitrile; 1-Cyano-5,5-difluoro-2-cyclohexanone; Cyclohexanecarbonitrile, 5,5-difluoro-2-oxo-
EINECS	Contact for details

Quality Control

Every batch of 5,5-Difluoro-2-Oxocyclohexanecarbonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive material from atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.