Description

2-(Methoxymethyl)-1-Pyrrolidinesulfonyl Chloride is a specialized sulfonyl chloride derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its reactivity as a versatile sulfonylation and coupling agent, enabling the efficient synthesis of complex sulfonamides and other functionalized molecules. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), especially for creating sulfonamide-based drug candidates with potential therapeutic applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the sulfonamide moiety is a critical functional group.
• Chemical Research & Development: A valuable tool for medicinal chemists in structure-activity relationship (SAR) studies and for constructing diverse compound libraries.
• Sulfonamide Library Production: Enables high-throughput parallel synthesis of sulfonamide derivatives for screening in drug discovery programs.
• Polymer Chemistry: Can be employed as a monomer or modifying agent in the synthesis of specialty polymers with specific sulfonyl-containing side chains.
• Material Science: Potential use in creating advanced materials, such as metal-organic frameworks (MOFs) or surface modifiers, where its reactive chloride group facilitates attachment.

Basic Information

Product Name	2-(Methoxymethyl)-1-Pyrrolidinesulfonyl Chloride
CAS No.	1308384-40-8
Molecular Formula	C6H12ClNO3S
Molecular Weight	213.68 g/mol
Synonyms	1-(Chlorosulfonyl)-2-(methoxymethyl)pyrrolidine; 2-(Methoxymethyl)pyrrolidine-1-sulfonyl chloride; N-(Chlorosulfonyl)-2-(methoxymethyl)azolidine; Pyrrolidine, 2-(methoxymethyl)-, 1-sulfonyl chloride; 1-Pyrrolidinesulfonyl chloride, 2-(methoxymethyl)-; 2-Methoxymethyl-1-pyrrolidinesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(Methoxymethyl)-1-Pyrrolidinesulfonyl Chloride is manufactured and tested under strict quality management systems. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles (via HPLC, NMR, etc.) is provided with each shipment to ensure it meets the rigorous standards required for research and process chemistry applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.