Description

1-Bromo-2-Fluoro-3-(Methoxymethyl)Benzene is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique substitution pattern, which provides distinct reactivity and steric properties for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, ligand synthesis, and material science.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis, enabling challenging cross-coupling and C-H activation reactions.
• Material Science Research: Employed in the creation of specialty monomers and polymers, such as liquid crystals or organic electronic materials, where the methoxymethyl group offers tunable solubility.
• Chemical Biology Probes: Utilized to synthesize fluorescent tags or photoaffinity labels for studying protein-ligand interactions and cellular processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-Bromo-2-Fluoro-3-(Methoxymethyl)Benzene
CAS No.	1307255-11-3
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	2-Bromo-1-Fluoro-3-(Methoxymethyl)Benzene; 3-Bromo-2-Fluorobenzyl Methyl Ether; 1-Bromo-2-fluoro-3-(methoxymethyl)benzene; Benzene, 1-bromo-2-fluoro-3-(methoxymethyl)-; (3-Bromo-2-fluorophenyl)methanol methyl ether
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Fluoro-3-(Methoxymethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency essential for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.