Description

6-Fluoroquinoline-8-Carboxylic Acid is a high-purity fluorinated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, where its unique fluorine substitution pattern enables fine-tuning of biological activity and physicochemical properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A vital synthon for the research and development of new drug candidates, particularly in antibiotic and anticancer therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom enhances stability and bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for complexing agents and catalysts in asymmetric synthesis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and fluorescent markers due to the quinoline core's photophysical properties.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	6-Fluoroquinoline-8-Carboxylic Acid
CAS No.	1306605-84-4
Molecular Formula	C10H6FNO2
Molecular Weight	191.16 g/mol
Synonyms	8-Quinolinecarboxylic acid, 6-fluoro-; 6-Fluoro-8-quinolinecarboxylic acid; 6-Fluoroquinoline-8-carboxylate; 1306605-84-4; 6-Fluoro-8-carboxyquinoline; 6-Fluoro-8-quinoline carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Fluoroquinoline-8-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.