Description

1-(2,3,6-Trifluorophenyl)Propan-2-One is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its trifluoromethylphenyl core offers unique electronic and steric properties, enabling the development of novel compounds with enhanced stability and bioactivity. This intermediate is critically important for research and production in the pharmaceutical and agrochemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to improved lipophilicity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, enhancing charge transport and thermal stability.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or host materials in next-generation display technologies.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with specific optical, thermal, or surface properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reactions and creating libraries of fluorinated compounds for screening.

Basic Information

Product Name	1-(2,3,6-Trifluorophenyl)Propan-2-One
CAS No.	1305324-34-8
Molecular Formula	C9H7F3O
Molecular Weight	188.15 g/mol
Synonyms	2-Propanone, 1-(2,3,6-trifluorophenyl)-; 1-(2,3,6-Trifluorophenyl)acetone; 2,3,6-Trifluorophenylacetone; 1-(2,3,6-Trifluorophenyl)-2-propanone; 2',3',6'-Trifluoropropiophenone; 3',4',6'-Trifluoropropiophenone; TFPP; Trifluoropropiophenone derivative
EINECS	Contact for details

Quality Control

Our 1-(2,3,6-Trifluorophenyl)Propan-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.