Description

Dl-Ap5 Sodium Salt CAS NO 1303993-72-7 is a high-purity biochemical reagent widely used in advanced life science research. This compound serves as a selective and potent antagonist of glutamate receptors, specifically targeting the NMDA receptor subtype, which is critical for studying neurological pathways. It is an essential tool for researchers in neuroscience, pharmacology, and cell biology investigating synaptic plasticity, excitotoxicity, and related neurological disorders.

Application

• Neurological Research: As a selective NMDA receptor antagonist for studying excitatory synaptic transmission, long-term potentiation (LTP), and long-term depression (LTD).
• Pharmacological Studies: Used in vitro and in vivo to model and investigate the mechanisms of neurodegenerative diseases and neuropathic pain.
• Cell Signaling Pathways: A key reagent for elucidating the role of glutamate receptors in intracellular calcium signaling and neuronal cell death (excitotoxicity).
• Biochemical Assay Development: Serves as a reference standard and active component in high-throughput screening assays for drug discovery targeting neurological conditions.
• Academic & Institutional Research: Fundamental tool for universities and research institutes conducting basic research on brain function and neurological disorders.

Basic Information

Product Name	Dl-Ap5 Sodium Salt
CAS No.	1303993-72-7
Molecular Formula	C5H8NNaO5P
Molecular Weight	216.08 g/mol
Synonyms	DL-2-Amino-5-phosphonopentanoic acid sodium salt; DL-AP5 Sodium Salt; DL-APV Sodium Salt; (RS)-2-Amino-5-phosphonopentanoic acid sodium salt; (±)-AP5 Sodium Salt; NMDA Receptor Antagonist AP5 Sodium Salt; DL-2-Amino-5-phosphonovaleric acid sodium salt
EINECS	Contact for details

Quality Control

Our Dl-Ap5 Sodium Salt is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and elemental analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.