Description

1-(5-Fluoropyridin-2-Yl)Cyclopropanecarboxylic Acid is a high-value fluorinated pyridine derivative and cyclopropane-containing building block essential for modern synthetic chemistry. This compound matters as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure imparts desirable metabolic stability and binding properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging the fluoropyridine moiety for enhanced bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for metal-catalyzed cross-coupling reactions.
• Advanced Material Precursor: Potential use in creating functionalized organic compounds for electronic or optical materials.

Basic Information

Product Name	1-(5-Fluoropyridin-2-Yl)Cyclopropanecarboxylic Acid
CAS No.	1302580-98-8
Molecular Formula	C9H8FNO2
Molecular Weight	181.16 g/mol
Synonyms	1-(5-Fluoropyridin-2-yl)cyclopropanecarboxylic acid; 1-(5-Fluoro-2-pyridinyl)cyclopropanecarboxylic acid; 2-(1-Carboxycyclopropyl)-5-fluoropyridine; Cyclopropanecarboxylic acid, 1-(5-fluoro-2-pyridinyl)-; 1302580-98-8; 5-Fluoro-2-(1-carboxycyclopropyl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(5-Fluoropyridin-2-Yl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.