Description

1-Fluorocyclobutane Methanol is a fluorinated cyclobutane derivative, a valuable building block in advanced organic synthesis. Its unique structure, featuring a fluorinated cyclobutyl ring attached to a hydroxymethyl group, makes it a versatile intermediate for introducing conformational rigidity and fluorine atoms into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the fluorocyclobutane moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts in asymmetric synthesis, leveraging the constrained cyclobutane geometry.
• Material Science Research: Investigated as a monomer or modifier for specialty polymers to impart unique physicochemical properties such as altered solubility or thermal stability.
• Fluorine Chemistry Research: An important substrate for studying C-F bond reactivity and for the synthesis of more complex fluorinated compounds in academic and industrial R&D settings.

Basic Information

Product Name	1-Fluorocyclobutane Methanol
CAS No.	1301207-68-0
Molecular Formula	C5H9FO
Molecular Weight	104.12 g/mol
Synonyms	(Fluorocyclobutyl)methanol; 1-Fluorocyclobutanemethanol; Cyclobutane methanol, 1-fluoro-; (1-Fluorocyclobutyl)methanol; Fluorocyclobutanemethanol; 1-Fluoro-cyclobutanemethanol; 1-Fluorocyclobutylcarbinol
EINECS	Contact for details

Quality Control

Our 1-Fluorocyclobutane Methanol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider maintaining under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.