Description

5-Fluoro-3-Iodo-2-Pivalamidoisonicotinic Acid is a high-purity, multi-functional heterocyclic building block designed for advanced pharmaceutical and agrochemical research. Its unique molecular structure, featuring fluorine and iodine substituents on a pivalamido-modified isonicotinic acid core, makes it a critical intermediate for synthesizing novel active compounds. This product is essential for medicinal chemists and R&D professionals in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new drug candidates or crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Employed in the development of advanced organic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Fluoro-3-Iodo-2-Pivalamidoisonicotinic Acid
CAS No.	1299607-63-8
Molecular Formula	C11H10F I N2O3
Molecular Weight	364.11 g/mol
Synonyms	2-Pivalamido-5-fluoro-3-iodoisonicotinic acid; 5-Fluoro-3-iodo-2-[(2,2-dimethylpropanoyl)amino]isonicotinic acid; 2-[(2,2-Dimethylpropanoyl)amino]-5-fluoro-3-iodopyridine-4-carboxylic acid; 1299607-63-8; 5-Fluoro-3-iodo-2-pivalamidoisonicotinic acid; 4-Pyridinecarboxylic acid, 2-[(2,2-dimethyl-1-oxopropyl)amino]-5-fluoro-3-iodo-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-Iodo-2-Pivalamidoisonicotinic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.