Description

4-Methyl-2-Propionylamino-Thiazole-5-Sulfonyl Chloride is a high-purity, specialized sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound is valued for its reactivity as a sulfonylation agent, enabling the introduction of the sulfonamide functional group into target molecules. It is primarily required by research and development laboratories and production facilities in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with sulfonamide moieties.
• Chemical Research & Development: Serves as a versatile reagent for constructing complex heterocyclic compounds and exploring new reaction pathways.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the production scale-up of specific APIs requiring this sulfonyl chloride derivative.
• Material Science: Potential building block for creating specialized polymers or functional materials with specific sulfonamide properties.

Basic Information

Product Name	4-Methyl-2-Propionylamino-Thiazole-5-Sulfonyl Chloride
CAS No.	1291490-19-1
Molecular Formula	C7H9N3O3S2Cl
Molecular Weight	282.74 g/mol
Synonyms	2-Propionamido-4-methylthiazole-5-sulfonyl chloride; 4-Methyl-2-propionylaminothiazole-5-sulfonyl chloride; 5-(Chlorosulfonyl)-4-methyl-2-(propionylamino)thiazole; 2-(Propionylamino)-4-methyl-1,3-thiazole-5-sulfonyl chloride; 4-Methyl-2-propionamidothiazole-5-sulfonyl chloride; Thiazole-5-sulfonyl chloride, 4-methyl-2-(propionylamino)-; 1291490-19-1
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Propionylamino-Thiazole-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FTIR and NMR, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.