Description

Amg 837 CAS NO 1291087-14-3 is a high-purity, small molecule chemical compound used as a key intermediate in advanced pharmaceutical research and development. This compound is critical for enabling the synthesis of novel therapeutic agents, particularly in targeted drug discovery programs. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in medicinal chemistry and preclinical studies.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic candidates.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological pathways and validate novel drug targets.
• Contract Manufacturing: Supplied to CDMOs for scale-up synthesis under current Good Manufacturing Practice (cGMP) conditions for clinical trial material production.
• Academic Research: Utilized in university and institutional labs for fundamental chemical and pharmacological research.

Basic Information

Product Name	Amg 837
CAS No.	1291087-14-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	AMG-837; AMG 837; 1291087-14-3; AG-837; AG 837; Amg837; AG837; (Chemical name to be confirmed)
EINECS	Contact for details

Quality Control

Our Amg 837 is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling using advanced techniques such as HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We can support development projects requiring compliance with research-grade or cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.