Description

Lpxc Inhibitor 1A is a potent and selective small molecule inhibitor targeting the LpxC enzyme, a key component in the biosynthesis of lipid A in Gram-negative bacteria. This compound is of significant value for research into novel antibacterial agents and the development of new therapeutic strategies against multidrug-resistant infections. It is primarily needed by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on microbiology, infectious disease, and antibiotic discovery.

Application

• Antibacterial Research: Serves as a critical tool compound for studying the lipid A biosynthesis pathway and validating LpxC as a therapeutic target.
• Mechanism of Action Studies: Used in biochemical and cellular assays to investigate bacterial resistance mechanisms and enzyme kinetics.
• Lead Optimization: Provides a structural scaffold for medicinal chemistry programs aimed at developing next-generation antibiotics with improved potency and pharmacokinetics.
• Infectious Disease Models: Employed in in vitro and in vivo studies to evaluate efficacy against a range of Gram-negative pathogens, including Pseudomonas aeruginosa and E. coli.
• High-Throughput Screening (HTS): Can be used as a reference standard in screening campaigns to identify new chemical entities with LpxC inhibitory activity.

Basic Information

Product Name	Lpxc Inhibitor 1A
CAS No.	1289620-49-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	LpxC Inhibitor 1A; LpxC-IN-1; 1289620-49-0; LpxC inhibitor; UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase inhibitor; Lipid A biosynthesis inhibitor; Antibacterial research compound
EINECS	Contact for details

Quality Control

Our Lpxc Inhibitor 1A is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques, including HPLC and NMR, to confirm identity and potency. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under inert atmosphere for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.