Description

2-Fluoro-4-(Methylthio)Nicotinaldehyde is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and methylthio substituents, makes it an essential precursor for creating complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Building block for developing new pesticides and herbicides with enhanced efficacy and selectivity.
• Material Science Research: Used in the creation of specialized ligands, catalysts, and functional organic materials.
• Chemical Biology Probes: Enables the synthesis of fluorinated probes for studying biological mechanisms and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in client-specific synthesis projects requiring fluorinated nicotinaldehyde scaffolds.

Basic Information

Product Name	2-Fluoro-4-(Methylthio)Nicotinaldehyde
CAS No.	1289172-46-8
Molecular Formula	C8H6FNO1S1
Molecular Weight	183.20 g/mol
Synonyms	2-Fluoro-4-(methylsulfanyl)nicotinaldehyde; 4-(Methylthio)-2-fluoronicotinaldehyde; 2-Fluoro-4-methylsulfanyl-pyridine-3-carbaldehyde; 3-Pyridinecarboxaldehyde, 2-fluoro-4-(methylthio)-; 2-Fluoro-4-(methylmercapto)nicotinaldehyde; 2-Fluoro-4-(methylthio)-3-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Methylthio)Nicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP starting materials and REACH compliance for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.