Description

2-Fluoro-5-(Methylthio)Nicotinaldehyde is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a methylthio substituent, makes it an essential precursor for creating novel compounds with tailored properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the fluorinated pyridine core.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials.
• Chemical Research & Development: A versatile reagent for exploring new fluorination reactions and heterocyclic chemistry.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.

Basic Information

Product Name	2-Fluoro-5-(Methylthio)Nicotinaldehyde
CAS No.	1289144-87-1
Molecular Formula	C8H6FNO1S
Molecular Weight	183.20 g/mol
Synonyms	5-(Methylthio)-2-fluoronicotinaldehyde; 2-Fluoro-5-(methylsulfanyl)pyridine-3-carbaldehyde; 3-Pyridinecarboxaldehyde, 2-fluoro-5-(methylthio)-; 2-Fluoro-5-methylsulfanyl-nicotinaldehyde; 2-Fluoro-5-(methylmercapto)nicotinaldehyde
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Methylthio)Nicotinaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.