Description

6-Methyl-4-Trifluoromethyl-Pyridine-3-Carbaldehyde is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and aldehyde functionalities make it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of novel organic electronic materials, liquid crystals, and functional polymers.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	6-Methyl-4-Trifluoromethyl-Pyridine-3-Carbaldehyde
CAS No.	1289103-14-5
Molecular Formula	C8H6F3NO
Molecular Weight	189.14 g/mol
Synonyms	4-(Trifluoromethyl)-6-methylpyridine-3-carboxaldehyde; 3-Formyl-6-methyl-4-(trifluoromethyl)pyridine; 6-Methyl-4-(trifluoromethyl)nicotinaldehyde; 6-Methyl-4-(trifluoromethyl)-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 6-methyl-4-(trifluoromethyl)-; 6-Methyl-4-trifluoromethyl-3-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Our production of 6-Methyl-4-Trifluoromethyl-Pyridine-3-Carbaldehyde adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor quality systems to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.