Description

2-(Dimethylamino)-4-(Trifluoromethyl)Benzaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl and dimethylamino functional groups. This compound matters as a critical building block for synthesizing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the trifluoromethyl group for improved efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and dyes due to its electron-donating and accepting properties.
• Fluorine Chemistry Building Block: Essential for introducing the trifluoromethyl moiety into complex molecular architectures in medicinal and synthetic chemistry.

Basic Information

Product Name	2-(Dimethylamino)-4-(Trifluoromethyl)Benzaldehyde
CAS No.	1289084-29-2
Molecular Formula	C10H10F3NO
Molecular Weight	217.19 g/mol
Synonyms	4-(Trifluoromethyl)-2-(dimethylamino)benzaldehyde; 2-(N,N-Dimethylamino)-4-(trifluoromethyl)benzaldehyde; 2-Dimethylamino-α,α,α-trifluoro-p-tolualdehyde; 4-(Trifluoromethyl)-2-(dimethylamino)benzenecarboxaldehyde; 2-(Dimethylamino)-α,α,α-trifluoro-p-tolualdehyde; p-(Trifluoromethyl)-o-(dimethylamino)benzaldehyde
EINECS	Contact for details

Quality Control

Our 2-(Dimethylamino)-4-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.