Description

1-Bromo-2-Fluoro-3-(Methylaminomethyl)Benzene is a high-purity, multi-functional aromatic building block of significant interest in advanced organic synthesis. Its core value lies in its unique substitution pattern, which provides distinct reactivity for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules requiring a halogenated, fluorinated, and amine-functionalized benzene core.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, and insecticides where the fluorine and bromine atoms can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, or organic electronic materials that require specific aromatic monomers.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and custom synthesis houses to build bespoke compounds for client projects.
• Fluorine Chemistry Studies: Acts as a model substrate in methodological development for reactions involving fluorinated arenes.

Basic Information

Product Name	1-Bromo-2-Fluoro-3-(Methylaminomethyl)Benzene
CAS No.	1287218-19-2
Molecular Formula	C8H9BrFN
Molecular Weight	218.07 g/mol
Synonyms	3-(Bromomethyl)-2-fluoro-N-methylaniline; 2-Fluoro-3-(methylaminomethyl)bromobenzene; 1-Bromo-2-fluoro-3-(N-methylaminomethyl)benzene; 3-(Aminomethyl)-2-fluorobenzyl bromide, N-methyl-; (2-Fluoro-3-(methylaminomethyl)phenyl)bromide; Benzenemethanamine, 3-(bromomethyl)-2-fluoro-N-methyl-; 1287218-19-2
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Fluoro-3-(Methylaminomethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.