Description

Bromindione-D4 CAS NO 1286965-30-7 is a high-purity, deuterium-labeled analog of the anticoagulant agent Bromindione. This stable isotope-labeled compound is essential for precise quantitative analysis and metabolic studies, providing unmatched accuracy in pharmacokinetic and bioanalytical research. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers for use as an internal standard in LC-MS/MS and GC-MS applications.

Application

• Primary use as an internal standard for the accurate quantification of Bromindione in biological matrices via mass spectrometry.
• Critical component in pharmacokinetic (PK) and bioequivalence studies to ensure data integrity and regulatory compliance.
• Facilitates drug metabolism and disposition (DMPK) research, aiding in the identification and quantification of metabolites.
• Enables high-precision therapeutic drug monitoring (TDM) in clinical research settings.
• Supports forensic and anti-doping analysis where definitive identification and quantification are required.
• Used in the development and validation of robust analytical methods in compliance with FDA, EMA, and ICH guidelines.

Basic Information

Product Name	Bromindione-D4
CAS No.	1286965-30-7
Molecular Formula	C19H11D4BrO3
Molecular Weight	Contact for details
Synonyms	2-(4'-Bromophenyl)-1,3-indandione-d4; 2-(4-Bromophenyl)-1H-indene-1,3(2H)-dione-d4; Bromindione (phenyl-d4); Bromindione-d4 Internal Standard; [D4]-Bromindione; 4'-Bromo-2-phenyl-1,3-indandione-d4; 2-(4-Bromobenzoyl)-1-indanone-d4
EINECS	Contact for details

Quality Control

Every batch of Bromindione-D4 is manufactured under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and isotopic enrichment. Our products are supplied with a comprehensive Certificate of Analysis (COA) detailing results from NMR, HPLC, and MS analysis, confirming chemical and isotopic purity suitable for use as a certified reference material. We support compliance with ICH Q2(R1) and other relevant regulatory guidelines for analytical procedure validation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.