Description

1H-Pyrrolo[2,3-B]Pyridin-2-Ylboronic Acid CAS NO 1286777-16-9 is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fused heterocyclic scaffolds found in drug candidates targeting various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient synthesis of biaryl and heterobiaryl structures, which are prevalent in many bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with complex heterocyclic cores.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and sensors.
• Chemical Biology & Proteomics: Can be utilized in the development of molecular probes and inhibitors for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridin-2-Ylboronic Acid
CAS No.	1286777-16-9
Molecular Formula	C9H9BN2O2
Molecular Weight	188.00 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridine-2-boronic acid; 2-(1H-Pyrrolo[2,3-b]pyridin-2-yl)boronic acid; 1H-Pyrrolo[2,3-b]pyridin-2-ylboronic acid; 7-Azaindole-2-boronic acid; 2-Borono-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-2-yl-B(OH)2; 2-(7-Azaindolyl)boronic acid; 1286777-16-9
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridin-2-Ylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (by HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via spectroscopic methods (NMR, IR), and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.