Description

n-Demethyl Trimebutine-D5 Hydrochloride is a deuterated isotopologue of a key pharmaceutical intermediate. This high-purity compound is essential for the development and validation of analytical methods in drug metabolism and pharmacokinetic (DMPK) studies. It is primarily used by research institutions and pharmaceutical companies engaged in the synthesis and quality control of deuterated active pharmaceutical ingredients (APIs) and their metabolites.

Application

• As a deuterated internal standard for the accurate quantification of trimebutine and its metabolites in biological matrices using LC-MS/MS.
• In pharmaceutical research and development for conducting stable isotope tracer studies to elucidate metabolic pathways.
• For the synthesis and characterization of advanced deuterated drug candidates and related substances.
• Use in quality control laboratories to ensure the accuracy and precision of analytical methods for related APIs.
• As a critical reference material in regulatory bioanalytical method validation to meet FDA and ICH guidelines.

Basic Information

Product Name	n-Demethyl Trimebutine-D5 Hydrochloride
CAS No.	1286632-72-1
Molecular Formula	C22H30D5NO4 • HCl
Molecular Weight	Contact for details
Synonyms	Trimebutine-d5 Metabolite Hydrochloride; 2-(Dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate-d5 Hydrochloride; 3,4,5-Trimethoxybenzoic Acid 2-(Dimethylamino)-2-phenylbutyl Ester-d5 Hydrochloride; Deuterated Trimebutine Metabolite HCl; Nor-Trimebutine-d5 HCl
EINECS	Contact for details

Quality Control

Our n-Demethyl Trimebutine-D5 Hydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for chemical purity and isotopic enrichment, NMR for structural confirmation, and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D5)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.