Description

[13C]-9-Methylfluorene-9-Carboxylic Acid CAS NO 1285695-14-8 is a stable isotope-labeled derivative of 9-methylfluorene-9-carboxylic acid, where a carbon-13 atom is incorporated into its molecular structure. This labeling is critical for applications requiring precise internal standards or metabolic pathway tracing in advanced analytical chemistry. It is primarily utilized by research scientists and process developers in the pharmaceutical, agrochemical, and material science industries for quantitative analysis and mechanistic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a crucial quantitative reference standard in LC-MS and GC-MS analysis for drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Pathway Tracing: Used in biomedical and environmental research to track the fate and transformation of fluorene-based compounds using isotope-ratio monitoring.
• Pharmaceutical Impurity Profiling: Enables accurate identification and quantification of process-related impurities and degradants in active pharmaceutical ingredient (API) development.
• Advanced Material Research: Acts as a labeled precursor or model compound in the synthesis and analysis of novel polymers or organic electronic materials.
• Environmental Analysis: Employed as a labeled surrogate in the detection and quantification of polycyclic aromatic hydrocarbon (PAH) derivatives in complex matrices.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Provides a non-radioactive tracer for structural elucidation and reaction monitoring studies.

Basic Information

Product Name	[13C]-9-Methylfluorene-9-Carboxylic Acid
CAS No.	1285695-14-8
Molecular Formula	C15H12O2 (with one 13C atom)
Molecular Weight	~225.26 g/mol (exact mass depends on 13C position)
Synonyms	9-Methyl-9H-fluorene-9-carboxylic-13C acid; 9-(Carboxy-13C)-9-methylfluorene; 13C Labeled 9-MFA; 9-Methylfluorene-9-carboxylic-13C acid; Isotopically labeled fluorene carboxylic acid; 13C9-Methylfluorene-9-carboxylic Acid; 9-Methyl-9-fluorenecarboxylic-13C Acid
EINECS	Contact for details

Quality Control

Every batch of [13C]-9-Methylfluorene-9-Carboxylic Acid is manufactured and analyzed under strict quality protocols to ensure isotopic and chemical purity for demanding research applications. Our quality system guarantees traceability and consistency. Comprehensive Certificates of Analysis (COA) are provided, detailing key parameters such as isotopic enrichment (typically >99 atom % 13C), chemical purity (by HPLC), and identity confirmation (by NMR and MS).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C
Chemical Purity (by NMR)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.