Description

4-(Benzyloxy)-3,5-Difluorobenzaldehyde is a high-purity fluorinated aromatic aldehyde building block. This compound matters for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals where the introduction of fluorine and a protected aldehyde group is critical.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in creating advanced herbicides and fungicides where the difluorobenzene moiety enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic and display material development.
• Organic Synthesis & Cross-Coupling Reactions: The aldehyde group is amenable to further transformations (e.g., reductive amination, condensation) for constructing complex molecular architectures.
• Fluorine Chemistry Research: A valuable substrate for studying the effects of fluorine substitution on reactivity and physical properties in organic molecules.

Basic Information

Product Name	4-(Benzyloxy)-3,5-Difluorobenzaldehyde
CAS No.	1285690-36-9
Molecular Formula	C14H10F2O2
Molecular Weight	248.22 g/mol
Synonyms	3,5-Difluoro-4-(phenylmethoxy)benzaldehyde; 3,5-Difluoro-4-(benzyloxy)benzaldehyde; 4-(Benzyloxy)-3,5-difluorobenzaldehyde; Benzaldehyde, 3,5-difluoro-4-(phenylmethoxy)-; 4-Benzyloxy-3,5-difluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-(Benzyloxy)-3,5-Difluorobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage or after opening. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.