Description

n-{[3-(Trifluoromethyl)Pyridin-2-Yl]Methylidene}Hydroxylamine is a specialized organic compound featuring a trifluoromethylpyridine core functionalized with a methylidene hydroxylamine group. This structure makes it a valuable high-purity building block and key intermediate in advanced chemical synthesis, particularly where the introduction of nitrogen-oxygen functionality and fluorine atoms is required. It is primarily utilized by pharmaceutical, agrochemical, and advanced material research and development teams seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Serves as a crucial precursor in the creation of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to develop new chelating ligands or catalyst systems.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as organic semiconductors or liquid crystals, where its specific molecular architecture can influence electronic properties.
• Chemical Biology Probe Synthesis: Acts as a building block for creating molecular probes and tool compounds used in biochemical and pharmacological research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific custom synthesis projects.

Basic Information

Product Name	n-{[3-(Trifluoromethyl)Pyridin-2-Yl]Methylidene}Hydroxylamine
CAS No.	1280538-35-3
Molecular Formula	C7H5F3N2O
Molecular Weight	190.12 g/mol
Synonyms	N-[(3-(Trifluoromethyl)pyridin-2-yl)methylidene]hydroxylamine; 2-Pyridinecarboxaldehyde, 3-(trifluoromethyl)-, oxime; (E/Z)-N-((3-(Trifluoromethyl)pyridin-2-yl)methylene)hydroxylamine; 3-(Trifluoromethyl)picolinaldehyde oxime; (3-Trifluoromethyl-2-pyridyl)methanal oxime; Building Block 1280538-35-3; Trifluoromethylpyridine hydroxylamine derivative
EINECS	Contact for details

Quality Control

Our n-{[3-(Trifluoromethyl)Pyridin-2-Yl]Methylidene}Hydroxylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.