Description

3-Fluoro-2-Methoxy-5-Nitropyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique electronic and steric properties imparted by the fluorine, methoxy, and nitro substituents, which make it a versatile precursor for creating complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Material Science Precursor: Serves as a building block for functionalized ligands in catalysis and for creating advanced organic electronic materials.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Fluoro-2-Methoxy-5-Nitropyridine
CAS No.	1279814-95-7
Molecular Formula	C6H5FN2O3
Molecular Weight	172.11 g/mol
Synonyms	5-Nitro-3-fluoro-2-methoxypyridine; 2-Methoxy-3-fluoro-5-nitropyridine; 3-Fluoro-2-methoxy-5-nitro-pyridine; Pyridine, 3-fluoro-2-methoxy-5-nitro-; 1279814-95-7; 3-Fluoro-5-nitro-2-methoxypyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-Methoxy-5-Nitropyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.