Description

1-[(6-Cyclohexyl-D11-4-Methyl-2-Oxo-1(2H)-Pyridinyl)Oxy]-1-Deoxy--D-Glucopyranuronic Acid is a high-purity, deuterated chemical intermediate of significant importance in advanced research and development. This compound is valued for its role as a stable isotope-labeled building block, enabling precise metabolic and pharmacokinetic studies. It is primarily sought after by pharmaceutical R&D teams, analytical laboratories, and specialty chemical manufacturers working on novel drug discovery and development programs.

Application

• Pharmaceutical Research: As a deuterium-labeled intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) for metabolic stability and tracer studies.
• Drug Metabolism & Pharmacokinetics (DMPK): Used as an internal standard or probe in mass spectrometry for accurate quantification and metabolite identification.
• Isotope Labeling: Serves as a key precursor for the preparation of deuterated analogs of bioactive molecules to study structure-activity relationships.
• Analytical Reference Standard: Employed as a certified reference material (CRM) for method development and validation in HPLC and LC-MS analysis.
• Biochemical Research: Utilized in enzymatic and receptor-binding assays where a non-radioactive, stable isotope label is required.
• Process Chemistry Development: Acts as a specialized intermediate for scaling up the production of deuterated drug candidates under GMP conditions.

Basic Information

Product Name	1-[(6-Cyclohexyl-D11-4-Methyl-2-Oxo-1(2H)-Pyridinyl)Oxy]-1-Deoxy--D-Glucopyranuronic Acid
CAS No.	1279033-13-4
Molecular Formula	C18H17D11NO8
Molecular Weight	~423.5 g/mol
Synonyms	1-Deoxy-1-[(6-cyclohexyl-D11-4-methyl-2-oxo-1(2H)-pyridinyl)oxy]-D-glucopyranuronic acid; Deuterated Cyclohexyl Methyl Oxopyridinyl Glucuronate; D11-Labeled Glucuronic Acid Conjugate; (6-Cyclohexyl-d11-4-methyl-2-oxo-1(2H)-pyridinyl) 1-deoxy-D-glucopyranosiduronic acid; Perdeuterocyclohexyl pyridone glucuronide; Stable Isotope-Labeled Glucuronide Metabolite Standard
EINECS	Contact for details

Quality Control

Our 1-[(6-Cyclohexyl-D11-4-Methyl-2-Oxo-1(2H)-Pyridinyl)Oxy]-1-Deoxy--D-Glucopyranuronic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chemical purity, isotopic enrichment (D11), and impurity profile. We adhere to relevant industry guidelines for advanced intermediates, and specifications can be tailored to meet specific research or cGMP requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Purity (D11, MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.