Description

L-2-Aminobutyric Acid-D6 is a stable isotope-labeled analog of the non-proteinogenic amino acid 2-aminobutyric acid, where six hydrogen atoms are replaced by deuterium. This high-purity compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring unparalleled accuracy and reliability in analytical measurements. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and academic institutions engaged in metabolomics, pharmacokinetic studies, and biomedical research where precise quantification is critical.

Application

• Quantitative Mass Spectrometry (MS) Internal Standard: Serves as a critical reference compound in LC-MS/MS and GC-MS analyses for accurate quantification of endogenous 2-aminobutyric acid and related metabolites.
• Biomedical and Metabolomics Research: Enables precise tracking and measurement of metabolic pathways, flux analysis, and biomarker discovery in complex biological samples.
• Pharmaceutical Development (DMPK/ADME): Used in drug metabolism and pharmacokinetics studies to monitor the disposition of drug candidates and their metabolites.
• Clinical Diagnostics: Facilitates the development of highly accurate diagnostic assays for metabolic disorders where 2-aminobutyric acid is a relevant analyte.
• Isotope Dilution Analysis: Provides the gold-standard method for achieving high precision and minimizing matrix effects in quantitative analytical chemistry.
• Neuroscience and Biochemical Research: Investigates the role of 2-aminobutyric acid as a neurotransmitter modulator and intermediate in various biochemical processes.

Basic Information

Product Name	L-2-Aminobutyric Acid-D6
CAS No.	1276197-51-3
Molecular Formula	C₄H₃D₆NO₂
Molecular Weight	109.15 g/mol
Synonyms	(2S)-2-Amino[3,3,4,4,5,5-D6]butanoic Acid; L-2-Amino[3,3,4,4,5,5-D6]butyric Acid; (S)-2-Aminobutyric Acid-D6; L-α-Aminobutyric Acid-D6; L-Homoalanine-D6; (S)-2-Aminobutanoic Acid-D6; Deuterated L-2-Aminobutyrate; Stable Isotope-Labeled ABA
EINECS	Contact for details

Quality Control

Our L-2-Aminobutyric Acid-D6 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for sensitive analytical applications. Each batch is thoroughly characterized by NMR, MS, and HPLC to confirm identity, chemical purity, and deuterium enrichment. A comprehensive Certificate of Analysis (COA) is provided, detailing all specifications and test results to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (D)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.