Description

1-(1-(5-Fluoropyridin-3-Ylsulfonyl)Piperidin-4-Yl)Ethanamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonylpiperidine-pyridine hybrid structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the design of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the design of potential kinase inhibitors, leveraging the fluoropyridine and sulfonamide motifs.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• Bioconjugation & Probe Synthesis: The primary amine functionality allows for conjugation to labels, tags, or other molecular entities to create chemical probes for biological studies.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to produce complex, high-value specialty chemicals for research purposes.

Basic Information

Product Name	1-(1-(5-Fluoropyridin-3-Ylsulfonyl)Piperidin-4-Yl)Ethanamine
CAS No.	1274122-74-5
Molecular Formula	C12H18FN3O2S
Molecular Weight	287.35 g/mol
Synonyms	4-(1-Aminoethyl)-1-(5-fluoropyridine-3-sulfonyl)piperidine; 1-[1-(5-Fluoropyridine-3-sulfonyl)piperidin-4-yl]ethan-1-amine; Ethanamine, 1-[1-[(5-fluoro-3-pyridinyl)sulfonyl]-4-piperidinyl]-; 1-(1-(5-Fluoropyridin-3-ylsulfonyl)piperidin-4-yl)ethanamine; 4-(1-Aminoethyl)-N-(5-fluoropyridin-3-yl)piperidine-1-sulfonamide
EINECS	Contact for details

Quality Control

Our 1-(1-(5-Fluoropyridin-3-Ylsulfonyl)Piperidin-4-Yl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.