Description

1-(1-(5-Fluoropyridin-3-Ylsulfonyl)Piperidin-2-Yl)-n-Methylmethanamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonylpiperidine-pyridine hybrid structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, especially in areas targeting central nervous system (CNS) disorders and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potential active pharmaceutical ingredients (APIs) for clinical research.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Employed in vitro and in vivo to study biological pathways and validate novel drug targets, particularly in neuroscience.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Reference Standard: Used as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	1-(1-(5-Fluoropyridin-3-Ylsulfonyl)Piperidin-2-Yl)-n-Methylmethanamine
CAS No.	1273851-05-0
Molecular Formula	C12H18FN3O2S
Molecular Weight	287.35 g/mol
Synonyms	N-Methyl-1-[1-[(5-fluoropyridin-3-yl)sulfonyl]piperidin-2-yl]methanamine; 1-(1-(5-Fluoropyridine-3-sulfonyl)piperidin-2-yl)-N-methylmethanamine; 1273851-05-0; 5-Fluoro-3-[(2-[(methylamino)methyl]piperidin-1-yl)sulfonyl]pyridine; CAS 1273851-05-0
EINECS	Contact for details

Quality Control

Our 1-(1-(5-Fluoropyridin-3-Ylsulfonyl)Piperidin-2-Yl)-n-Methylmethanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the results against our stringent internal specifications. We support development and commercial projects with material produced in compliance with cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.