Description

8-Methyl-Isoquinoline-5-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile sulfonylation reagent, enabling the introduction of the 8-methyl-isoquinoline-5-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides with specific modes of action.
• Peptide Modification: Employed as a sulfonylation agent for modifying amino acid side chains in peptide chemistry and bioconjugation.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of advanced polymers and functional materials.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying enzyme function and protein interactions.
• Dye and Pigment Chemistry: Acts as an intermediate in the production of specialized dyes and optical materials.

Basic Information

Product Name	8-Methyl-Isoquinoline-5-Sulfonyl Chloride
CAS No.	1273567-42-2
Molecular Formula	C₁₀H₈ClNO₂S
Molecular Weight	241.69 g/mol
Synonyms	8-Methylisoquinoline-5-sulfonyl chloride; 5-Isoquinolinesulfonyl chloride, 8-methyl-; 8-Methyl-5-isoquinolinesulfonyl chloride; 8-Methyl-isoquinolin-5-sulfonyl chloride; 1273567-42-2
EINECS	Contact for details

Quality Control

Our 8-Methyl-Isoquinoline-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.