Description

5-Fluoro-2-(Piperidin-2-Yl)Pyridine is a high-value, nitrogen-containing heterocyclic compound that serves as a critical building block in modern synthetic chemistry. Its unique fused pyridine-piperidine structure with a fluorine substituent makes it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Research: Used in developing new generation pesticides and herbicides, where the fluorine atom and heterocyclic core can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating novel nitrogen-donor ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probe Synthesis: Employed in medicinal chemistry to build molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or functional additive for advanced polymers and functional materials.

Basic Information

Product Name	5-Fluoro-2-(Piperidin-2-Yl)Pyridine
CAS No.	1270471-87-8
Molecular Formula	C10H13FN2
Molecular Weight	180.22 g/mol
Synonyms	2-(2-Pyridinyl)-5-fluoropiperidine; 5-Fluoro-2-(2-piperidinyl)pyridine; 2-(5-Fluoropyridin-2-yl)piperidine; 5-Fluoro-2-piperidin-2-ylpyridine; 1270471-87-8; 5-Fluoro-2-(2-piperidyl)pyridine; 2-(Piperidin-2-yl)-5-fluoropyridine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Piperidin-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.