Description

2-(4-Fluoro-2-Methylphenyl)Pyrrolidine is a high-purity fluorinated pyrrolidine derivative, a key building block in modern synthetic organic chemistry. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated motifs into target structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, where the fluorinated aromatic moiety can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom to improve pesticidal activity and environmental profile.
• Ligand and Catalyst Development: Serves as a backbone for creating chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or organic semiconductors, where fluorination tunes electronic properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and bio-conjugation reagents in diagnostic and biochemical research.

Basic Information

Product Name	2-(4-Fluoro-2-Methylphenyl)Pyrrolidine
CAS No.	1270412-03-7
Molecular Formula	C11H14FN
Molecular Weight	179.24 g/mol
Synonyms	2-(4-Fluoro-2-methylphenyl)pyrrolidine; 4-Fluoro-2-methyl-α-(pyrrolidin-1-ylmethyl)benzene; 1-[(4-Fluoro-2-methylphenyl)methyl]pyrrolidine; Pyrrolidine, 2-(4-fluoro-2-methylphenyl)-; 2-(4-Fluoro-o-tolyl)pyrrolidine; 4-Fluoro-2-methylbenzylpyrrolidine
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Fluoro-2-Methylphenyl)Pyrrolidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.