Description

2-Pyridinepropanoic Acid, α-Amino-5-Fluoro-, (αs)- is a high-purity, non-natural amino acid derivative featuring a fluorinated pyridine core. This compound is valued for its role as a sophisticated chiral building block in advanced pharmaceutical synthesis, enabling the development of novel therapeutic agents. It is primarily required by research institutions and pharmaceutical companies engaged in the discovery and development of new drugs, particularly in areas requiring fluorinated bioactive molecules.

Application

• Key pharmaceutical intermediate for the synthesis of active pharmaceutical ingredients (APIs).
• Chiral precursor in asymmetric synthesis for creating enantiomerically pure compounds.
• Building block for fluorinated bioactive molecules in medicinal chemistry research.
• Starting material for the development of protease inhibitors and other enzyme-targeting drugs.
• Research chemical in academic and industrial R&D for studying structure-activity relationships (SAR).
• Potential use in synthesizing diagnostic agents or imaging probes.

Basic Information

Product Name	2-Pyridinepropanoic Acid, α-Amino-5-Fluoro-, (αs)-
CAS No.	1270264-67-9
Molecular Formula	C8H9FN2O2
Molecular Weight	184.17 g/mol
Synonyms	(αS)-α-Amino-5-fluoro-2-pyridinepropanoic acid; (S)-2-Amino-3-(5-fluoropyridin-2-yl)propanoic acid; 5-Fluoro-D-homopyridylalanine; 2-Pyridinepropanoic acid, α-amino-5-fluoro-, (αS)-; (S)-3-(5-Fluoropyridin-2-yl)-L-alanine; D-2-(5-Fluoropyridyl)alanine; A fluorinated pyridylalanine derivative
EINECS	Contact for details

Quality Control

Our production of 2-Pyridinepropanoic Acid, α-Amino-5-Fluoro-, (αs)- adheres to stringent quality protocols suitable for pharmaceutical R&D. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. For long-term stability, storage at 2-8°C is recommended. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.