Description

1-Chloro-3-Fluoro-5-Iodobenzene is a high-purity halogenated benzene derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it an essential intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by R&D chemists and process development scientists for applications in medicinal chemistry, material science, and the synthesis of specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of fluorinated and iodinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, leveraging the halogen atoms for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings, enabling complex molecular architecture construction.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.
• Ligand and Catalyst Design: Used to synthesize sophisticated ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	1-Chloro-3-Fluoro-5-Iodobenzene
CAS No.	1270019-81-2
Molecular Formula	C6H3ClFI
Molecular Weight	256.44 g/mol
Synonyms	3-Chloro-5-Fluoroidobenzene; 5-Chloro-1-Fluoro-3-Iodobenzene; 1-Fluoro-3-Chloro-5-Iodobenzene; 3-Fluoro-5-Chloroidobenzene; Benzene, 1-chloro-3-fluoro-5-iodo-; 3-Chloro-5-fluoro-1-iodobenzene; 5-Fluoro-3-chloroidobenzene; 1-Chloro-3-fluoro-5-iodo-benzene
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Fluoro-5-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical properties are provided with every shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.