Description

2'-(Trifluoromethyl)-2,4'-Bipyrimidine is a specialized heterocyclic building block featuring a bipyrimidine core substituted with a trifluoromethyl group. This compound is valued for its unique electronic properties and structural rigidity, making it a critical intermediate in advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Synthesis: Acts as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand in Catalysis: Potential use as a chelating ligand in transition metal catalysis due to its bipyrimidine structure.

Basic Information

Product Name	2'-(Trifluoromethyl)-2,4'-Bipyrimidine
CAS No.	1269292-51-4
Molecular Formula	C9H5F3N4
Molecular Weight	226.16 g/mol
Synonyms	2-(Trifluoromethyl)-2,4'-bipyrimidine; 2,4'-Bipyrimidine, 2'-(trifluoromethyl)-; 2'-(Trifluoromethyl)-2,4'-bipyrimidine; 2-(2-Pyrimidinyl)-4-(trifluoromethyl)pyrimidine; 4-(Trifluoromethyl)-2,2'-bipyrimidine
EINECS	Contact for details

Quality Control

Our 2'-(Trifluoromethyl)-2,4'-Bipyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.