Description

4-Oxo-1,2,5,6-Tetrahydro-4H-Pyrrolo[3,2,1-Ij]Quinoline-8-Sulfonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive sulfonyl chloride functional group. This compound is critical for the synthesis of complex molecules, offering a versatile handle for constructing sulfonamide linkages under controlled conditions. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Sulfonamide Library Synthesis: Used in combinatorial chemistry and high-throughput screening to create diverse libraries of sulfonamide-containing compounds for biological evaluation.
• API Development: Serves as a precursor in the multi-step synthesis of complex target molecules for potential therapeutic applications.
• Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for studying enzyme function and protein-protein interactions.
• Agrochemical Research: Intermediate in the development of new agrochemicals, such as herbicides or fungicides, where the sulfonamide moiety is a common pharmacophore.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers with unique properties.

Basic Information

Product Name	4-Oxo-1,2,5,6-Tetrahydro-4H-Pyrrolo[3,2,1-Ij]Quinoline-8-Sulfonyl Chloride
CAS No.	1268026-52-3
Molecular Formula	C13H10ClNO3S
Molecular Weight	295.74 g/mol
Synonyms	8-Sulfonylchloride-4-oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline; 4H-Pyrrolo[3,2,1-ij]quinoline-8-sulfonyl chloride, 1,2,5,6-tetrahydro-4-oxo-; 1,2,5,6-Tetrahydro-4-oxo-4H-pyrrolo[3,2,1-ij]quinoline-8-sulfonyl chloride; Pyrroloquinoline sulfonyl chloride derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-Oxo-1,2,5,6-Tetrahydro-4H-Pyrrolo[3,2,1-Ij]Quinoline-8-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.