Description

1-(4-Fluorophenyl)-4-Methyl-2-Oxo-1,2-Dihydropyridine-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridone-carbonitrile core structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Active Pharmaceutical Ingredient (API) Development: Integral in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.
• Chemical Reference Standard: Serves as an analytical standard for quality control and method development in API production.

Basic Information

Product Name	1-(4-Fluorophenyl)-4-Methyl-2-Oxo-1,2-Dihydropyridine-3-Carbonitrile
CAS No.	1267968-10-4
Molecular Formula	C13H9FN2O
Molecular Weight	228.22 g/mol
Synonyms	4-Methyl-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile; 1-(4-Fluorophenyl)-4-methyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile; 3-Cyano-1-(4-fluorophenyl)-4-methyl-2(1H)-pyridinone; 1-(4-Fluorophenyl)-4-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile; 1267968-10-4
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)-4-Methyl-2-Oxo-1,2-Dihydropyridine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.