Description

Lisavanbulin is a potent and selective small molecule inhibitor with significant research and development interest in the pharmaceutical sector. This compound matters as a key intermediate and active pharmaceutical ingredient (API) in the development of novel therapeutic agents, particularly in oncology. It is needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and academic institutions engaged in preclinical and clinical-stage drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of advanced drug candidates.
• Oncology Research: Used as a reference standard and active material in biological assays and mechanism-of-action studies for cancer therapeutics.
• API Development: Employed in the formulation and process development stages for new chemical entities (NCEs).
• Preclinical Studies: Utilized in pharmacokinetic, pharmacodynamic, and toxicology evaluations in animal models.
• Chemical Biology Probe: Acts as a tool compound to investigate specific biological pathways and target validation.
• GMP Manufacturing: Supplied as a starting material or intermediate for the production of clinical trial materials under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	Lisavanbulin
CAS No.	1263384-43-5
Molecular Formula	C₂₀H₂₀N₄O₃
Molecular Weight	364.40 g/mol
Synonyms	BAL101553; (S)-2-(1H-Indazol-5-yl)-6-(4-(4-methylpiperazin-1-yl)phenyl)-1,2,4-triazolo[1,5-a]pyridine; 2-(1H-Indazol-5-yl)-6-[4-(4-methyl-1-piperazinyl)phenyl][1,2,4]triazolo[1,5-a]pyridine; (S)-BAL101553; Lisavanbulin free base
EINECS	Contact for details

Quality Control

Our Lisavanbulin is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are supported by comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR, MS), and residual solvent analysis. Certificates of Analysis (COA) are provided with each shipment, and we can supply material that meets specific customer requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Assay	97.0% - 103.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.