Description

(3-(Trifluoromethoxy)Phenyl)Methanesulfonyl Chloride is a specialized organosulfur compound featuring a reactive sulfonyl chloride group and a trifluoromethoxy-substituted aromatic ring. This unique structure makes it a valuable high-purity building block for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily utilized by process chemists and R&D professionals in the fine chemical and life science industries who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing sulfonamide or sulfonate ester functional groups.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethoxy moiety.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with specific surface properties.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for metal catalysis or as a scaffold for functionalized catalysts in asymmetric synthesis.
• Chemical Biology Probes: Useful for modifying proteins, peptides, or other biomolecules to study biological pathways or create diagnostic tools.

Basic Information

Product Name	(3-(Trifluoromethoxy)Phenyl)Methanesulfonyl Chloride
CAS No.	1263274-68-5
Molecular Formula	C8H6ClF3O3S
Molecular Weight	274.64 g/mol
Synonyms	3-(Trifluoromethoxy)benzenemethanesulfonyl chloride; α-(Trifluoromethoxy)benzenemethanesulfonyl chloride; (3-Trifluoromethoxyphenyl)methanesulfonyl chloride; m-(Trifluoromethoxy)phenylmethanesulfonyl chloride; 1-(Trifluoromethoxy)-3-(chlorosulfonylmethyl)benzene; (3-(Trifluoromethoxy)phenyl)methylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of (3-(Trifluoromethoxy)Phenyl)Methanesulfonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.