Description

Difluoro-Pyridin-4-Yl-Acetic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound is essential for introducing both a difluoropyridine moiety and a reactive acetic acid functional group into target molecules, enabling precise modulation of physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the difluoropyridine unit can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring fluorinated heterocyclic architectures.

Basic Information

Product Name	Difluoro-Pyridin-4-Yl-Acetic Acid
CAS No.	1263178-28-4
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	2-(2,6-Difluoropyridin-4-yl)acetic acid; 4-Pyridineacetic acid, 2,6-difluoro-; (2,6-Difluoropyridin-4-yl)acetic Acid; 2,6-Difluoro-4-pyridylacetic Acid; 1263178-28-4; 2,6-Difluoropyridine-4-acetic acid; Difluoropyridylacetic Acid
EINECS	Contact for details

Quality Control

Our Difluoro-Pyridin-4-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its acidic nature, handle with appropriate engineering controls and personal protective equipment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.