Description

Hpi-1 Hydrate is a high-purity chemical compound, identified by CAS number 1262770-72-8, that serves as a potent and selective inhibitor of the hypoxia-inducible factor (HIF) pathway. This compound is crucial for researchers and developers in life sciences, offering a valuable tool for modulating cellular responses to low oxygen conditions. It is primarily utilized in pharmaceutical R&D, biochemical research, and as a reference standard in analytical laboratories.

Application

• Pharmaceutical Research & Development: As a key biochemical tool for studying hypoxia signaling pathways, cancer metabolism, and angiogenesis.
• Biochemical Assays: Used as a selective inhibitor in in vitro and cell-based assays to investigate HIF-1α stability and activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and other analytical techniques.
• Preclinical Studies: Employed in animal model research to explore therapeutic interventions for conditions involving pathological hypoxia.
• Academic Research: A critical reagent for universities and research institutes focusing on molecular biology, oncology, and cardiovascular diseases.

Basic Information

Product Name	Hpi-1 Hydrate
CAS No.	1262770-72-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HIF-1 Inhibitor; HPI-1; (E)-N-(4-Hydroxyphenyl)-2-(pyridin-2-yl)ethenesulfonamide hydrate; HIF-1α Inhibitor; Hypoxia-inducible factor 1 inhibitor; 2-(2-Pyridinyl)ethenesulfonamide, N-(4-hydroxyphenyl)-, (E)-, hydrate
EINECS	Contact for details

Quality Control

Our Hpi-1 Hydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤5.0%
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.