Description

2,5,6-Trifluoro-3-(Hydroxymethyl)Pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a hydroxymethyl group and multiple fluorine atoms, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and functional materials that require fluorinated aromatic components.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems due to its derivatizable functional groups.

Basic Information

Product Name	2,5,6-Trifluoro-3-(Hydroxymethyl)Pyridine
CAS No.	1262415-64-4
Molecular Formula	C6H4F3NO
Molecular Weight	175.10 g/mol
Synonyms	3-(Hydroxymethyl)-2,5,6-trifluoropyridine; 2,5,6-Trifluoropyridine-3-methanol; (2,5,6-Trifluoropyridin-3-yl)methanol; 2,5,6-Trifluoro-3-pyridinemethanol; 3-Hydroxymethyl-2,5,6-trifluoropyridine; 2,5,6-Trifluoro-3-pyridylcarbinol
EINECS	Contact for details

Quality Control

Our 2,5,6-Trifluoro-3-(Hydroxymethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.