Description

2-(2,5-Difluorophenyl)-5-Hydroxypyridine is a high-purity fluorinated pyridine derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its molecular structure, featuring both a difluorophenyl group and a hydroxypyridine moiety, makes it an essential precursor for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the synthesis of complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its fluorinated aromatic system.
• Material Science: Serves as a monomer or precursor for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: A versatile reagent for constructing complex heterocyclic compounds and for introducing fluorinated aromatic systems into target molecules.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and exploring new chemical spaces.
• Contract Manufacturing (CMO/CDMO): Supplied to contract development and manufacturing organizations for scale-up and GMP production of client molecules.

Basic Information

Product Name	2-(2,5-Difluorophenyl)-5-Hydroxypyridine
CAS No.	1261937-03-4
Molecular Formula	C11H7F2NO
Molecular Weight	207.18 g/mol
Synonyms	5-Hydroxy-2-(2,5-difluorophenyl)pyridine; 2-(2,5-Difluorophenyl)pyridin-5-ol; [2,5-Difluorophenyl]-5-hydroxypyridine; 5-Pyridinol, 2-(2,5-difluorophenyl)-; 1261937-03-4; 2-(2,5-Difluorophenyl)-5-pyridinol
EINECS	Contact for details

Quality Control

Our 2-(2,5-Difluorophenyl)-5-Hydroxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.