Description

3-Amino-5-Fluoropyridin-2-Ol Hcl is a high-purity, halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique chemical structure, which introduces both amino and fluoro substituents onto the pyridine core, enabling precise molecular modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific pyridine functionalization.

Basic Information

Product Name	3-Amino-5-Fluoropyridin-2-Ol Hcl
CAS No.	1261923-85-6
Molecular Formula	C5H6FN2O·HCl
Molecular Weight	164.57 g/mol (Free base) 201.03 g/mol (Hydrochloride salt)
Synonyms	2-Hydroxy-3-amino-5-fluoropyridine hydrochloride; 5-Fluoro-2-hydroxy-3-pyridinamine hydrochloride; 3-Amino-5-fluoro-2-pyridinol hydrochloride; 3-Amino-5-fluoro-2(1H)-pyridinone hydrochloride; 5-Fluoro-3-amino-2-pyridinol HCl; 2-Pyridinol, 3-amino-5-fluoro-, hydrochloride; 3-Amino-5-fluoropyridin-2-ol HCl salt
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-5-Fluoropyridin-2-Ol Hcl is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.