Description

2-Methyl-5-(Trifluoromethoxy)Benzenesulfonylchloride is a specialized aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, acting as a versatile electrophile for introducing the sulfonamide moiety and a precursor for other sulfonyl-based reagents. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the production of specialty polymers, dyes, and functional materials requiring sulfonyl groups.
• Chemical Research: A versatile reagent in academic and industrial R&D for constructing complex molecular architectures and exploring new reaction pathways.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalytic processes.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethoxy)Benzenesulfonylchloride
CAS No.	1261852-46-3
Molecular Formula	C8H6ClF3O3S
Molecular Weight	274.65 g/mol
Synonyms	5-(Trifluoromethoxy)-2-methylbenzenesulfonyl chloride; 2-Methyl-5-(trifluoromethoxy)benzene-1-sulfonyl chloride; 1-Methyl-4-(trifluoromethoxy)benzene-2-sulfonyl chloride; 2-Methyl-α,α,α-trifluoro-p-anisolesulfonyl chloride; 5-Methyl-2-(trifluoromethoxy)benzenesulfonyl chloride; 2-Methyl-5-trifluoromethoxybenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethoxy)Benzenesulfonylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.