Description

8-Fluoroquinolin-5-Ol is a high-purity fluorinated quinoline derivative, a versatile and valuable building block in advanced organic synthesis. Its core value lies in its unique molecular structure, which serves as a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate the fluorinated quinoline scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluorinated quinolone antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport layers.
• Chemical Synthesis: Acts as a versatile fluorinated synthon for complex molecule construction in medicinal chemistry and process R&D.
• Ligand & Catalyst Development: The quinoline nitrogen and hydroxyl group make it a candidate for designing novel metal-chelating ligands and catalysts.
• Fluorescent Probe Synthesis: Utilized in the creation of fluorophore tags and sensors for biochemical and diagnostic applications.

Basic Information

Item	Details
Product Name	8-Fluoroquinolin-5-Ol
CAS No.	1261845-15-1
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	5-Hydroxy-8-fluoroquinoline; 8-Fluoro-5-hydroxyquinoline; 8-Fluoro-5-quinolinol; 5-Quinolinol, 8-fluoro-; 8-Fluoroquinolin-5-ol; 1261845-15-1
EINECS	Contact for details

Quality Control

Our 8-Fluoroquinolin-5-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee batch-to-batch consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be kept in the dark.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.