Description

2,6-Difluoropyridine-3-Sulfonyl Chloride (Wx192273) is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. This compound matters as a key sulfonylation reagent, enabling the precise introduction of the sulfonyl chloride functional group into complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

This versatile sulfonyl chloride derivative is a critical intermediate in the synthesis of sophisticated molecules. Its primary applications include:

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides with enhanced efficacy.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialized polymers and functional materials.
• Chemical Research: An invaluable reagent for medicinal chemistry and process chemistry for constructing complex heterocyclic systems.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	2,6-Difluoropyridine-3-Sulfonyl Chloride (Wx192273)
CAS No.	1261843-52-0
Molecular Formula	C5H2ClF2NO2S
Molecular Weight	213.59 g/mol
Synonyms	3-Pyridinesulfonyl chloride, 2,6-difluoro-; 2,6-Difluoropyridine-3-sulfonyl chloride; 2,6-Difluoro-3-pyridinesulfonyl chloride; 1261843-52-0; Wx192273; 3-Sulfonyl chloride-2,6-difluoropyridine; 2,6-Difluoro-3-sulfonylchloridopyridine
EINECS	Contact for details

Quality Control

Our 2,6-Difluoropyridine-3-Sulfonyl Chloride is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.