Description

2-Bromo-3-Methoxybenzene-1-Sulfonyl Chloride is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. Its core value lies in its reactive sulfonyl chloride and bromo-methoxy substituted aromatic structure, enabling precise molecular construction. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides with tailored activity profiles.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation, labeling biomolecules, or creating activity-based probes.
• Cross-Coupling Reactions: The bromo substituent makes it a suitable substrate for palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination.
• Sulfonylation Agent: Reacts with amines, alcohols, and organometallic reagents to introduce the sulfonyl functional group.

Basic Information

Product Name	2-Bromo-3-Methoxybenzene-1-Sulfonyl Chloride
CAS No.	1261818-17-0
Molecular Formula	C7H6BrClO3S
Molecular Weight	285.54 g/mol
Synonyms	1-Bromo-2-methoxy-6-(chlorosulfonyl)benzene; 3-Bromo-2-methoxybenzenesulfonyl chloride; 2-Methoxy-3-bromobenzenesulfonyl chloride; 6-Bromo-2-methoxybenzenesulfonyl chloride; 2-Bromo-3-methoxybenzenesulfonyl chloride; Benzenesulfonyl chloride, 2-bromo-3-methoxy-; 1261818-17-0
EINECS	Contact for details

Quality Control

Our production of 2-Bromo-3-Methoxybenzene-1-Sulfonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.