Description

4-Cyano-2-Methoxybenzene-1-Sulfonylchloride is a specialized aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its dual reactive sites—the sulfonyl chloride and cyano groups—which enable precise molecular construction for high-value intermediates. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides that require specific sulfonyl moiety integration.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional coatings.
• Chemical Biology Probes: Employed in the design of activity-based probes (ABPs) and affinity labels for target protein identification.
• Dye and Pigment Manufacturing: Intermediate for producing advanced colorants with enhanced lightfastness and chemical stability.
• Custom Synthesis & Contract Manufacturing: A versatile starting material for bespoke chemical synthesis projects in R&D and pilot-scale production.

Basic Information

Product Name	4-Cyano-2-Methoxybenzene-1-Sulfonylchloride
CAS No.	1261791-90-5
Molecular Formula	C8H6ClNO3S
Molecular Weight	231.66 g/mol
Synonyms	2-Methoxy-4-cyanobenzenesulfonyl chloride; 4-Cyano-2-methoxybenzenesulfonyl chloride; 2-Methoxy-4-cyanobenzene-1-sulfonyl chloride; 4-Cyano-o-anisylsulfonyl chloride; 2-Methoxy-4-cyanophenylsulfonyl chloride; 4-Cyano-2-methoxyphenylsulfonyl chloride; 1-(Chlorosulfonyl)-2-methoxy-4-cyanobenzene; 2-Methoxy-4-cyano-1-sulfonylchlorobenzene
EINECS	Contact for details

Quality Control

Our production of 4-Cyano-2-Methoxybenzene-1-Sulfonylchloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot is characterized using advanced analytical techniques, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.