Description

1-Bromo-2-(Bromomethyl)-3-(Difluoromethyl)Benzene is a versatile and highly functionalized aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of reactive bromine and difluoromethyl groups, enabling precise molecular construction for complex target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring difluoromethyl or aryl bromide motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the difluoromethyl group can enhance lipophilicity and biological activity.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organocatalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the creation of novel monomers or functional units for advanced polymers and organic electronic materials.
• Fluorine Chemistry: An important substrate for studying and applying fluorination reactions and incorporating fluorine atoms into complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis houses serving the life sciences sector with tailored, high-purity chemical entities.

Basic Information

Product Name	1-Bromo-2-(Bromomethyl)-3-(Difluoromethyl)Benzene
CAS No.	1261791-24-5
Molecular Formula	C8H6Br2F2
Molecular Weight	299.94 g/mol
Synonyms	2-Bromo-1-(bromomethyl)-3-(difluoromethyl)benzene; 3-(Difluoromethyl)-1,2-bis(bromomethyl)benzene; 1,2-Bis(bromomethyl)-3-(difluoromethyl)benzene; Benzene, 1-bromo-2-(bromomethyl)-3-(difluoromethyl)-; α,α'-Dibromo-3-(difluoromethyl)-o-xylene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-(Bromomethyl)-3-(Difluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. Handle and store under an inert atmosphere if prolonged storage is required to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.